Fascination Circa pentobarbital sodium
Fascination Circa pentobarbital sodium
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At least one minute is necessary to determine the full effect of intravenous pentobarbital. If necessary, additional small increments of the drug may be given up to a total of from 200 to 500 mg for normal adults.
Capable of producing all levels of CNS depression—from mild sedation to hypnosis to deep coma to death.
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Metabolism: Pentobarbital undergoes first-pass metabolism Durante the liver. Pentobarbital is metabolized predominantly by the hepatic microsomal enzymes.
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Variable; patient-dependent and may vary occasionally within same patient. About 15 minutes following IV administration.
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Pentobarbital administration is through IM, IV, or oral routes. For IM administration, injecting no more than 5 mL and only into a large muscle to avoid tissue irritation or necrosis is advised.
The onset of action for oral or rectal administration varies from 20 to 60 minutes. For IM administration, the onset of action is slightly faster. Following IV administration, the onset of action ranges from almost immediately for pentobarbital sodium to 5 minutes more info for phenobarbital sodium.
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MAOI prolong the effects of barbiturates probably because metabolism of the barbiturate is inhibited.
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All drugs may cause side effects. However, many people have mai side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling sleepy.